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Adolescent intermittent alcohol exposure: dysregulation of thrombospondins and synapse formation are associated with decreased neuronal density in the adult hippocampus

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Low-oxygen incubations (5% or 1% O 2 ) were carried out in a Ruskinn SCI-tive workstation

The trials yielded mixed results and provided only partial validation for a neurotrophic- based PD treatment, while underscoring multiple issues raised by this type of therapy, including toxicity, inconsistent effectiveness, and the likely need to deliver drug to both the cell body area and terminal fields

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